The rest of the #realtimechemcarnival posts

Hi again,

Apologies for the delay in posting the last #realtimechemcarnival roundup. It has been a hectic time in the lab and at home!

@Fluorogrol contributed with his post on the oddities of scientific publishing, by reminding us that ” there’s free, and then there’s free“.

Katherine (@KJHaxton) then gave us a glimpse into her outreach life with her summary of a Chemistry at Work event for schools.

So that is it for the 2014 #realtimechemcarnival. See you again next year for another superb #realtimechem week.

Jess

 

#Realtimechemcarnival 2014 Day 2 and 3 Roundup

This year’s blog carnival has shone the light on a few chemistry blogs that I previously did not know existed. It is great to see so many new (to me) bloggers in the chem-blogosphere. Keep it up all. The more the merrier!

Here are the posts from Tues 24th and Weds 25th June.

1) Tom (@TRBranson) started us off with his awesome take on the supervisor-student relationship during thesis writing time.  I had many a comment on my thesis drafts, but I don’t think I was ever told that I was “fundamentally wrong”! Thanks for sharing, Tom.

2) Jess (@chemicaljess) wasn’t far behind her with post on intentions during a PhD. Her blog is a great place to read about the trials and tribulations of a PhD. Definitely worth a read for those just starting their PhD journey.

3) One of the prolific bloggers from last year’s  #realtimechemcarnival, Joaquin (@JoaquinBarroso), has again joined in with his post on his summer interns. It will be great to see the progress that these students make over the summer. Please do keep us up-to-date Joaquin!

4) Since the kind guys over at ChemDraw were kind enough to let me try out their new 2014 version, the least I could do was let them know what I thought of it.

5) Julia (@ochemprep) joins the party with her post on Praying for an Epiphany where she shares her story from undergrad to start-up founder.

Keep up the excellent #realtimechem work everyone and remember to let me know if you think I have missed any carnival posts.

#realtimechemcarnival – New ChemDraw: What do I think?

A slightly different post in aid of the #realtimechemcarnival but hopefully useful to someone!

I currently use ChemDraw 13 Pro at work. This has very basic features and is really only useful for drawing out reaction schemes and checking molecular weights. At my previous workplace, I had ChemDrawUltra 2010. This had a lot of useful features like “convert name to structure” and NMR prediction, which were really useful tools, especially as I was writing my PhD thesis at the time.

Recently, I was given the chance to trial the new ChemBioDrawUltra 14.0. I expected this to be a better, flashier version of ChemDrawUltra 2010 and, indeed, it is. It has pretty much all the same useful tools as ChemDrawUltra 2010 but it also has some new features, which I have had fun playing around with.

What do I particularly like about this new version?

1) BioDraw tools – our group is very interdisciplinary. We currently have people working with biocatalysts and we were very pleased to see updated BioDraw tools (a lot more choice and much more detailed) and a Biopolymer tool bar so that peptide/DNA chains can be drawn. I have a feeling the bio people in the lab will be wanting to borrow my laptop in the coming months!

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2) Structure Tool bar – this is a useful addition as it means I don’t keep having to go up to the structure menu. It contains the commonly used NMR prediction, naming and clean-up icons, amongst others.

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3) Scifinder addition – I thought this was a bit of a gimmick but it has made my life easier. I am currently writing a literature review and this has certainly made that quicker to write. It is as simple as drawing the structure, clicking on search > search SciFinder (via my library login page).

What I would like to see in future versions?

A tool bar for flow chemists – synthetic chemists are embracing flow chemistry more and more so it would be great to see some tools which would allow us to draw schemes of detailed flow set-ups.

Overall, I really liked this version. I will keep updating this post as I find more features that I like (or dislike). I got this version on a free trial, I am not sure, however, that I would pay the full price for it but I hope some employers do!

 

#Realtimechemcarnival 2014 Day 1 roundup

Hi all,

I hope you are all enjoying #realtimechem week! My week started with a house move and trip to Ikea so I am a little behind but from what I have seen so far, there has been a huge variety in the content of the tweets from people all over the world. Keep it up tweeps.

Monday gave us some really amazing blog posts, so thank you, bloggers, for getting involved and contributing.

1) Harm reduction – an interesting post on the rise of ecstasy derivatives by Craig (@Sci_McInnes).

2) The ever wonderful Laura-Jane (@laurajane0103) has started up her first chemistry-themed blog in aid of #realtimechem week. Her introductory post is a video snapshot into a day in the life of Laura Jane.

3) At The Dose Makes the Poison, Kevin (@forensictoxguy) gives us an overview of drug detection in urine.

4) A new (to me) blogger, Martin (@MartinStoermer), from Chemistry and Computers, shares their views on The trouble with Cha, (aka cyclehexylalanine).

5) Ellen (@ChemistLN) joins in on the video blogging by giving us a tour of her lonely lab.

Thanks to all that contributed to the awesome blog posts for day 1 of #realtimechem week. Do let me know if you think I have missed any or if you want to host a post of your own here. I shall be writing some of my own this week, so do watch this space.

Back to the lab for me.

Jess

#Realtimechem Blog Carnival

realtimechemcarnival2014

 

As Dr Jay has mentioned, we shall be doing #realtimechemcarnival during #realtimechem week again this year. For more information about #realtimechem week, read Jay’s FAQ.

You can blog about absolutely anything chemistry related - the stranger, the better!  Once you have blogged, either email me the link at theorganicsolutionblog at gmail dot com or link on Twitter using the hashtag #realtimechemcarnival. If I can, I will then post the day’s carnival posts here but if not I will definitely do a roundup at the end of the week. For some inspiration, do take a look at the 2013 entries .

If you have any questions about the carnival, don’t hesitate to get in touch!

Jess (@jessthechemist)

P.s Thanks to Jay for all his artwork!

 

Elemental chemistry

Hello world!

I thought I would interrupt this unplanned blog hiatus with a post about elements, which was inspired by a Twitter conversation with Dr Tom.

Which elemental form of the chemical elements have you used in the lab?

I believe my number is a lowly 10 although I am sure I have forgotten some.

Hydrogen (H), carbon (C), oxygen (O3), fluorine (F2), sodium (Na), magnesium (Mg), bromine (Br2), iridium (Ir), tin (Sn), iodine (I2).

Tom’s was a more impressive 12, including Samarium.

 

p.s I have obviously also used nitrogen and argon as inert gases in reactions and helium as a GC carrier gas but I don’t feel they count as I haven’t manipulated them into something new.

p.p.s oxygen has been added as I forgot that I have had plenty of experience with stinky ozone.

My top 10 chemistry papers of 2013

Having already contributed to the top 10 chemistry blog posts of 2013 over at The Sceptical Chymist, I thought I would highlight my top 10 chemistry publications of the year here. Current trendy chemistry seems to be nano-blah blah and MOFs but I am a flow/organic/process chemist so papers on these themes appear on the list below.

1) The most interesting and exciting publication of the year has to be Fujita’s Nature Article on X-ray analysis using porous complexes. This allows the determination of crystal structures without the need for crystallization of the actual sample molecules.

2) Baran’s Ingenol paper, in one of those luxury journals, was pretty darn impressive! Only 14 steps with cheap starting materials. The man is a legend.

3) As someone that works on catalytic processes, it was great to see Milstein publish an efficient method for the synthesis of carboxylic acids, without the need for stoichiometric amounts of toxic metals. It is always good to see publications describing a new method for a simple but valuable process.

4) You can always rely on MacMillan for a good read. This publication on the one-step synthesis of Plavix was no different.

5) If chemists can find an efficient way of capturing and utilizing CO2, the planet would be much happier. This publication on the Ni-catalysed direct carboxylation of benzyl halides with carbon dioxide is a great example of how we can use carbon dioxide to make synthetically useful building blocks.

6) My favourite fluorine paper of the year was this Science paper on the synthesis of fluorinated natural products using synthetic biology. I always enjoy reading inter-disciplinary work and this was no different.

7) My research is in chiral amine synthesis so this publication on the reduction of amides to amines was immediately appealing to me. The paper describes the reduction of primary, secondary and tertiary amides using a commercially available, air and moisture tolerant non-metal catalyst. Very cool.

8) I am always partial to a flow chemistry paper. Anything from the Ley, Jamison and Seeberger groups is worth reading but this recent overview of how to apply flow chemistry by Seeberger and McQuade really caught my eye.

9) The award for scariest paper of the year (as highlighted over at In the Pipeline) has to go to this work on mercury azides.

10) Interested in sustainable/green chemistry? Then the Sanofi solvent selection guide is one for you. I find OPRD to be a bit hit or miss at times but this is actually a super reference guide.

So this is my top 10. What is yours? Use the #chemclub2013 hashtag (sorry for stealing your hashtag, Andrew) on twitter to share your favourite paper of 2013!